In order to address the problem that the mutation in the current fuzzing has certain blindness and the samples generated by the mutation mostly pass through the same high-frequency paths, a binary fuzzing method based on light-weight program analysis technology was proposed and implemented. Firstly, the target binary program was statically analyzed to filter out the comparison instructions which hinder the sample files from penetrating deeply into the program during the fuzzing process. Secondly, the target binary program was instrumented to obtain the specific values of the operands in the comparison instructions, according to which the real-time comparison progress information for each comparison instruction was established, and the importance of each sample was measured according to the comparison progress information. Thirdly, the real-time path coverage information in the fuzzing process was used to increase the probability that the samples passing through rare paths were selected to be mutated. Finally, the input files were directed and mutated by the comparison progress information combining with a heuristic strategy to improve the efficiency of generating valid inputs that could bypass the comparison checks in the program. The experimental results show that the proposed method is better than the current binary fuzzing tool AFL-Dyninst both in finding crashes and discovering new paths.